Androxene and reform and that was used as a way to bond these things so this is an example where you have a channel made out of agarose gel and then you can bond it to another layer of agarose by just elevating this temperature to about 60 or 70 degrees or so so this works fine but then you don't necessarily want to expose cells to elevated temperatures and so on so this is a nice proof-of-concept but not necessarily a practical way for all the kinds of things that you want to do right others also use 3d printing and so in this particular case you have print of alternate materials or two materials one which is a collagen layer and then another one which is a gelatin layer and the idea being that you can then wash off the gelatin while the collagen forms the three-dimensional structure so these are some examples of channels made in that particular fashion the again this was another manifestation of the layer-by-layer approach in in fabrication the only issue with this is that you have to wash off these things and when the channel network becomes too complex or too small washing off becomes much more difficult now that example was 3d printing using a scaffold that is made out of sugar so it's almost like making cotton candy the idea behind this is that you can build a 3d printer which can create three-dimensional structures in sugar and and that can then be dipped into bath containing cells and ECM and then subsequently you can delete it and then you can dissolve the sugar away in order to create a profusion Network so again that was it's a goo

https://mumycares.com/androxene/